Anti-MAdCAM-1-Conjugated Nanocarriers Delivering Quantum Dots Enable Specific Imaging of Inflammatory Bowel Disease.
Marta TruffiMarta SevieriLucia MorelliMatteo MonieriSerena MazzucchelliLuca SorrentinoRaffaele AlleviArianna BonizziPietro ZerbiBeatrice MarchiniErika LonghiGianluca Matteo SampietroFrancesco ColomboDavide ProsperiMiriam ColomboFabio CorsiPublished in: International journal of nanomedicine (2020)
P@QD-MdC NPs efficiently detected bowel inflammation foci, accurately following the expression pattern of MAdCAM-1. Fine-tuning of this nanoconjugate with appropriate imaging agents offers a promising non-invasive tool for specific IBD diagnosis.