PathoSPOT genomic epidemiology reveals under-the-radar nosocomial outbreaks.
Ana Berbel CabanTheodore R PakAjay OblaAmy C DupperKieran I ChackoLindsey FoxAlexandra MillsBrianne CiferriIrina OussenkoColleen BeckfordMarilyn ChungRobert SebraMelissa SmithSarah ConollyGopi PatelAndrew KasarskisMitchell J SullivanDeena R AltmanHarm van BakelPublished in: Genome medicine (2020)
We demonstrate that PathoSPOT genomic surveillance enables the detection of complex transmission chains that are not readily apparent from epidemiological data and that contribute significantly to morbidity and mortality, enabling more effective intervention strategies.
Keyphrases
- copy number
- randomized controlled trial
- public health
- electronic health record
- risk factors
- loop mediated isothermal amplification
- big data
- label free
- methicillin resistant staphylococcus aureus
- klebsiella pneumoniae
- computed tomography
- magnetic resonance
- real time pcr
- machine learning
- gene expression
- dna methylation
- genome wide
- infectious diseases
- pseudomonas aeruginosa
- deep learning
- drug resistant
- data analysis