Adipose Tissue Composition in Obesity and After Bariatric Surgery.
Gian Franco AdamiFederico CarboneFabrizio MontecuccoGiovanni CameriniRenzo CorderaPublished in: Obesity surgery (2020)
The adipose tissue is a complex organ that regulates food intake and energy expenditure as well as induces low-grade inflammation. This review deals with changes in the composition and activity of the adipose organ after bariatric surgery, focusing on epicardial and ectopic fat and on relationships between white and brown adipose tissues. Postoperative improvements of ectopic fat and epicardial fat size and composition account for the metabolic recovery and the decreased cardiovascular risk. Following Roux-en-Y gastric bypass or biliopancreatic diversion, a proportional increase in the size and activity of the metabolically active brown adipose tissue was observed, most likely related to the postoperative rearrangement of the entero-hormonal pattern with an increase of GLP-1 production: this aspect would promote the postoperative weight loss and maintenance of post-surgery benefits.
Keyphrases
- adipose tissue
- roux en y gastric bypass
- weight loss
- insulin resistance
- low grade
- gastric bypass
- bariatric surgery
- patients undergoing
- high fat diet
- obese patients
- high grade
- polycystic ovary syndrome
- minimally invasive
- oxidative stress
- glycemic control
- weight gain
- coronary artery bypass
- gene expression
- high fat diet induced
- fatty acid
- body mass index
- drug induced
- physical activity
- atrial fibrillation