DNMT3B Expression Might Contribute to Abnormal Methylation of RASSF1A in Lager Colorectal Adenomatous Polyps.

Xianmei MengNa LiuYanbin JiaKerui GongJingjie ZhangWei ZhangGuo Shao Tong Dang

Published in: Gastroenterology research and practice (2020)

These results suggest that the overexpression of DNMT3B may contribute to a role in the genesis of CAPs through the hypomethylation of chromosomes in the whole cell and promoter hypermethylation of RASSF1A.

Keyphrases

dna methylation
genome wide
gene expression
poor prognosis
single cell
transcription factor
cell therapy
cell proliferation
stem cells
long non coding rna
binding protein
bone marrow