Pathological significance and prognostic significance of FES expression in bladder cancer vary according to tumor grade.

Akihiro AsaiYasuyoshi MiyataKosuke TakeharaShigeru KandaShin-Ichi WatanabePeter A GreerHideki Sakai

Published in: Journal of cancer research and clinical oncology (2017)

FES appeared to act as a suppressor of carcinogenesis, being associated with low tumor grade in the overall patient group. However, its expression correlated with cancer aggressiveness and poor outcome in high-grade bladder cancer. FES, therefore, represents a potential therapeutic target and useful prognostic factor for such patients.

Keyphrases

prognostic factors
high grade
poor prognosis
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
papillary thyroid
case report
binding protein
low grade
long non coding rna
squamous cell carcinoma
patient reported outcomes