Physical exercise consequences on memory in obesity: A systematic review.
Ricardo Augusto Leoni De SousaLetícia Gomes SantosPaulo Maurício LopesBruno Raphael Ribeiro CavalcanteAlex Cleber Improta CariaRicardo Cardoso CassilhasPublished in: Obesity reviews : an official journal of the International Association for the Study of Obesity (2021)
Obesity is associated with changes in memory. Thus, the aim of this systematic review was to investigate the physical exercise consequences on memory in obesity. A search was carried out in the PubMed, Lilacs, and Scielo databases with the following descriptors: "physical exercise," "memory," and "obesity." A total of 16 studies were analyzed in this review. Low, moderate, and high intensity exercise training showed positive effects on memory in patients with obesity (100%). The animal models of obesity used in their physical exercise protocols: treadmill (72.7%) or wheel running (27.3%). Most of the animal studies (81.8%) revealed positive effects of the physical exercise protocol on memory in obesity. Mouse was the most commonly used animal (54.5%), and a 60% high-fat diet (HFD) was the most commonly method used to induce obesity (82%). We did not identify any knockout model of obesity that was used to evaluate memory and used physical exercise as the main intervention. Thus, exercise training, independently if it is resistance or endurance training, seems to be an excellent intervention to prevent and inhibit cognitive impairment and memory loss on obese patients and animal models of obesity.
Keyphrases
- insulin resistance
- weight loss
- metabolic syndrome
- high fat diet
- high fat diet induced
- type diabetes
- high intensity
- weight gain
- systematic review
- working memory
- skeletal muscle
- randomized controlled trial
- bariatric surgery
- adipose tissue
- cognitive impairment
- obese patients
- body mass index
- physical activity
- case control