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Chlorogenic Acid Suppresses miR-155 and Ameliorates Ulcerative Colitis through the NF-κB/NLRP3 Inflammasome Pathway.

Junhao ZengDengqing ZhangXiaoyu WanYuanling BaiChengfu YuanTing WangDing YuanChangcheng ZhangChaoqi Liu
Published in: Molecular nutrition & food research (2020)
These findings indicate that CGA prevented colitis by downregulating miR-155 expression and inactivating the NF-κB/NLRP3 inflammasome pathway in macrophages. The current study has promising therapeutic implications in the treatment of UC.
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