New-onset seizures: an unusual neurologic manifestation of rheumatoid arthritis.
Omair Ali KhanSadia AslamFatemeh MohammadrezaeiRita Dennise Moncayo WilchesJoseph MehrabiMatania YehounatanSapna KumariSehajpreet SinghMaryam AhmadiDaniel MasriSarita KonkaYevgeniya MargulisPublished in: Oxford medical case reports (2024)
Rheumatoid arthritis (RA) is a chronic inflammatory condition primarily affecting the musculoskeletal system but can often involve other organ systems as well. Rheumatoid meningitis is a rare central nervous system (CNS) manifestation of RA characterized by pachymeningeal and leptomeningeal enhancement. Herein, we present a case of a 64-year-old male who presented with left lower extremity weakness and witnessed seizures. The diagnostic work-up, including lumbar puncture, brain MRI and meningeal biopsy ruled out malignancy and were consistent with the diagnosis of rheumatoid meningitis. The patient was discharged on high-dose steroids along with anti-seizure medications. On subsequent follow-up visits, the patient remained seizure-free.
Keyphrases
- rheumatoid arthritis
- disease activity
- cerebrospinal fluid
- rheumatoid arthritis patients
- high dose
- temporal lobe epilepsy
- case report
- ankylosing spondylitis
- interstitial lung disease
- ultrasound guided
- magnetic resonance imaging
- low dose
- minimally invasive
- oxidative stress
- resting state
- stem cell transplantation
- blood brain barrier
- white matter
- contrast enhanced
- computed tomography
- small cell lung cancer
- functional connectivity
- magnetic resonance
- fine needle aspiration
- subarachnoid hemorrhage
- drug induced