Diffuse alveolar hemorrhage in childhood-onset systemic lupus erythematosus: a severe disease flare with serious outcome.
Gabriela BlayJoaquim C RodriguesJuliana C O FerreiraGabriela N LealNatali W GormezanoGlaucia V NovakRosa M R PereiraMaria T TerreriClaudia S MagalhãesBeatriz C MolinariAna P SakamotoNadia E AikawaLucia M A CamposTaciana A P FernandesGleice ClementeOctavio A B PeracchiVanessa BugniRoberto MariniSilvana B SacchettiLuciana M CarvalhoMelissa M FragaTânia C M CastroValéria C RamosEloisa BonfáClovis Artur Almeida da Silvanull nullPublished in: Advances in rheumatology (London, England) (2018)
This was the first study to demonstrate that DAH, although not a disease activity score descriptor, occurred in the context of significant moderate/severe cSLE flare. Importantly, we identified that this condition was associated with serious disease flare complicated by sepsis with high mortality rate.