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The landscape of chromatin accessibility in skeletal muscle during embryonic development in pigs.

Jingwei YueXinhua HouXin LiuLigang WangHongmei GaoFuping ZhaoLijun ShiLiangyu ShiHua YanTianyu DengJianfei GongLixian WangLongchao Zhang
Published in: Journal of animal science and biotechnology (2021)
This work indicates that chromatin accessibility plays an important regulatory role in the embryonic muscle development of pigs and regulates the temporal and spatial expression patterns of key genes in muscle development by influencing the binding of transcription factors. Our results contribute to a better understanding of the regulatory dynamics of genes involved in pig embryonic skeletal muscle development.
Keyphrases
  • skeletal muscle
  • transcription factor
  • genome wide
  • insulin resistance
  • gene expression
  • dna damage
  • poor prognosis
  • oxidative stress
  • genome wide identification
  • single cell
  • long non coding rna