EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study.
Zhaonian HaoDongsheng GuoPublished in: BMC cancer (2019)
EGFR mutation indicates increasing infiltration of specific types of immune cells and poor prognosis in lower-grade glioma. Alteration of immune microenvironment since the EGFR mutation might influence the survival of glioma. We also provided a novel evidence and indicator of PD-1 inhibitor application in glioma.