The clinicopathological significance of Thrombospondin-4 expression in the tumor microenvironment of gastric cancer.

Kenji KurodaMasakazu YashiroTomohiro SeraYurie YamamotoYukako KushitaniAtsushi SugimotoSyuhei KushiyamaSadaaki NishimuraShingo ToganoTomohisa OkunoTatsuro TamuraTakahiro ToyokawaHiroaki TanakaKazuya MugurumaMasaichi Ohira

Published in: PloS one (2019)

THBS4 is expressed on CAFs in the gastric cancer microenvironment. THBS4 from CAFs is associated with the metastasis of cancer cells, and is a useful prognostic indicator for gastric cancer patients.

Keyphrases

poor prognosis
stem cells
binding protein