Efficacy and tolerability of lithium for the treatment of acute mania in children with bipolar disorder: A systematic review: A report from the ISBD-IGSLi joint task force on lithium treatment.
Anne C DuffyNaomi HefferSarah Margaret GooddayArielle WeirScott PattenGin S MalhiAndrea CiprianiPublished in: Bipolar disorders (2018)
Limited data suggests that lithium may be an effective and tolerable treatment for some forms of paediatric mania. However, lithium is clearly inferior in efficacy to risperidone in prepubertal patients diagnosed with protracted manic/mixed episodes and comorbid ADHD. There is a lack of data concerning the efficacy and tolerability of lithium as an acute treatment for classical mania in adolescents and important clinical issues remain unaddressed.
Keyphrases
- bipolar disorder
- young adults
- emergency department
- major depressive disorder
- end stage renal disease
- physical activity
- liver failure
- intensive care unit
- chronic kidney disease
- randomized controlled trial
- attention deficit hyperactivity disorder
- ejection fraction
- big data
- hepatitis b virus
- peritoneal dialysis
- prognostic factors
- working memory
- replacement therapy