Semaglutide and blood pressure: an individual patient data meta-analysis.
Cormac KennedyPeter HayesArrigo Francesco Giuseppe CiceroStephan DobnerCarel W le RouxJohn William McEvoyLina ZgagaMartina HennessyPublished in: European heart journal (2024)
This IPD analysis of three large RCTs found blood pressure reductions with semaglutide in participants with hypertension that were similar to those seen in all trial participants. This finding may in part be due to concurrent reductions to anti-hypertensive medications. These results suggest that semaglutide is a useful adjunctive treatment for patients with hypertension and obesity.
Keyphrases
- blood pressure
- hypertensive patients
- systematic review
- heart rate
- metabolic syndrome
- insulin resistance
- type diabetes
- clinical trial
- weight loss
- study protocol
- case report
- meta analyses
- blood glucose
- phase iii
- big data
- randomized controlled trial
- phase ii
- adipose tissue
- locally advanced
- skeletal muscle
- double blind
- placebo controlled