Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open-Label, Randomized, Bayesian Noninferiority Trial.

Paul A BroganBarbara ArchHelen HickeyJordi AntónEste IglesiasEileen BaildamKamran MahmoodGavin ClearyElena MoraitisCharalampia PapadopoulouMichael W BeresfordPhil RileySelcan DemirSeher SenerGiovanna CuledduDyfrig A HughesPavla DolezalovaLisa V HampsonJohn WhiteheadDavid JayneNicola RupertoCatrin Tudur-SmithDespina Eleftheriou

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2021)

The present results, taken together with prior opinion, indicate that rates of remission induction in childhood PAN are similar with MMF treatment and CYC treatment, and MMF treatment might be associated with better health-related quality of life than CYC treatment.

Keyphrases

randomized controlled trial
rheumatoid arthritis
open label
high dose
young adults
phase iii
systemic lupus erythematosus
ulcerative colitis