MicroRNA expression in JAG1/Notch-activated periodontal ligament stem cells.

Promphakkon KulthanaamondhitaChatvadee KornsuthisoponAjjima ChansaenrojVorapat TrachooJeeranan ManokawinchokeLakshman SamaranayakeSupreda Suphanantachat Srithanyarat Thanaphum Osathanon

Published in: BDJ open (2024)

The research concludes that several miRNAs are differentially expressed in jagged-1 treated PDLSCs. In translational terms the differential functionality of these miRNAs offer promise for the development of targeted regenerative materials that are necessary for managing lost tissue replacement in periodontal diseases.

Keyphrases

stem cells
poor prognosis
cell therapy
cancer therapy
mesenchymal stem cells
cell proliferation
big data