Cerebrospinal α-Synuclein Oligomers Reflect Disease Motor Severity in DeNoPa Longitudinal Cohort.
Nour K MajbourIlham Y AbdiMohammed DaknaTamara WickeElisabeth LangHouda Y Ali MoussaMercy A ThomasClaudia TrenkwalderBared Safieh-GarabedianTakahiko TokudaBrit MollenhauerOmar El-AgnafPublished in: Movement disorders : official journal of the Movement Disorder Society (2021)
Longitudinal transitions of CSF biomarkers over disease progression might not occur linearly and are susceptible to disease state. CSF oligomeric-α-synuclein levels appear to increase with diseases severity and reflect PD motor rather than cognitive trajectories. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
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