Uric acid induced hepatocytes lipid accumulation through regulation of miR-149-5p/FGF21 axis.

Shenghui ChenDan ChenHua YangXinyu WangJinghua WangCheng-Fu Xu

Published in: BMC gastroenterology (2020)

Uric acid significantly up-regulated the expression of miR-149-5p in hepatocytes and induced hepatocytes lipid accumulation via regulation of miR-149-5p/FGF21 axis.

Keyphrases

uric acid
metabolic syndrome
liver injury
drug induced
high glucose
diabetic rats
poor prognosis
transcription factor
endothelial cells
long non coding rna