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Memory-like Differentiation Enhances NK Cell Responses to Melanoma.

Nancy D MarinBradley Aaron KrasnickMichelle Becker-HapakLeah ConantSimon P GoedegebuureMelissa M Berrien-ElliottKeenan J RobbinsJennifer A FoltzMark FosterPamela WongCelia C CubittJennifer TranChristopher B WetzelMiriam T JacobsAlice Y ZhouDavid A Russler-GermainLynne MarsalaTimothy SchappeRyan C FieldsTodd A Fehniger
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Blood NK cells from allogeneic HD or patients with advanced melanoma can be differentiated into ML NK cells for use as a novel immunotherapeutic treatment for advanced melanoma, which warrants testing in early-phase clinical trials.
Keyphrases
  • nk cells
  • clinical trial
  • skin cancer
  • stem cell transplantation
  • bone marrow
  • basal cell carcinoma
  • working memory
  • randomized controlled trial
  • open label
  • hematopoietic stem cell
  • phase ii