The effect of levocarnitine supplementation on dialysis-related hypotension: A systematic review, meta-analysis, and trial sequential analysis.

Api ChewcharatPol ChewcharatWeitao LiuJacqueline CelliniElizabeth A PhippsJill A Melendez YoungSagar U Nigwekar

Published in: PloS one (2022)

Supplementing oral L-carnitine for at least three months above 4,200 mg/week helps prevent dialysis-related hypotension. L-carnitine supplementation may ameliorate muscle cramps. Further well-powered studies are required to conclude this benefit.

Keyphrases

systematic review
chronic kidney disease
end stage renal disease
case control
clinical trial
skeletal muscle
meta analyses
randomized controlled trial
phase ii