Physostigmine reversal of delirium from second generation antipsychotic exposure: a retrospective cohort study from a regional poison center.
Ann M ArensHamdi Sheikh SaidBrian E DriverJon B ColePublished in: Clinical toxicology (Philadelphia, Pa.) (2024)
In this study, physostigmine appears to be a safe and effective treatment for antimuscarinic delirium from second generation antipsychotic exposure. Further studies are needed to validate the safety and effectiveness of physostigmine for this indication.