Corneal epithelial differentiation of human pluripotent stem cells generates ABCB5 + and ∆Np63α + cells with limbal cell characteristics and high wound healing capacity.

Meri VattulainenTanja IlmarinenTaina ViheriäläVilma JokinenHeli Skottman

Published in: Stem cell research & therapy (2021)

cells with limbal characteristics, indicates hPSC-derived cells can be utilized as a valuable cell source for the treatment of patients afflicted corneal blindness due to LSCD.

Keyphrases

induced apoptosis
cell cycle arrest
wound healing
pluripotent stem cells
single cell
endoplasmic reticulum stress
oxidative stress
endothelial cells
signaling pathway
optical coherence tomography
stem cells
mesenchymal stem cells