β-CATENIN is a positive prognostic marker for HPV-positive head and neck squamous cell carcinoma.
Stefan StoiberFaris F BrkicTobias MaierJulia SchnoellElisabeth GurnhoferGregor HeiduschkaLorenz Kadletz-WankeLukas KennerPublished in: Journal of cancer research and clinical oncology (2023)
Based on these findings, we postulate that β-CATENIN expression could serve (potentially in conjunction with other WBC pathway members) as a marker for better survival outcomes in patients with HPV-positive HNSCC. However, it is evident that future studies on bigger cohorts are warranted.