Longitudinal Measurements of Glucocerebrosidase activity in Parkinson's patients.

Roy N AlcalayPavlina WolfMing Sum Ruby ChiangKarolina HelesicovaXiaokui Kate ZhangKalpana MerchantSamantha J HuttenClemens ScherzerChelsea Caspell-GarciaCornelis BlauwendraatTatiana M ForoudKelly NudelmanZiv Gan OrTanya SimuniLana M ChahineOren LevyDandi ZhengGen LiSergio Pablo Sardinull null

Published in: Annals of clinical and translational neurology (2020)

GCase activity is associated with GBA genotype, WBC count, and among p.E326K variant carriers, with PD status. Reduced activity may also be associated with worse phenotype but longer follow up is required to confirm this observation.

Keyphrases

end stage renal disease
ejection fraction
cross sectional
patient reported outcomes