Opioid analgesia and severity of acute pancreatitis: An international multicentre cohort study on pain management in acute pancreatitis.

Sanjay Pandanaboyana Cecilie Siggaard Knoph Søren Schou OlesenMichael JonesJames LucocqJayanta SamantaRupjyoti Talukdar Gabriele Capurso Enrique de MadariaDhiraj YadavAjith K SiriwardenaJohn WindsorAsbjørn Mohr DrewesManu Nayarnull null

Published in: United European gastroenterology journal (2024)

Opioid treatment increased the risk of more severe acute pancreatitis only when administered after admission day or for 6 days or more. Future randomised studies should re-evaluate whether opioids might be safe in acute pancreatitis.

Keyphrases

pain management
chronic pain
clinical trial
study protocol
emergency department
double blind
randomized controlled trial
early onset
open label
combination therapy
drug induced