A mood state-specific interaction between kynurenine metabolism and inflammation is present in bipolar disorder.

Seline van den AmeeleAlexander Ln van NuijsFoon Yin LaiJeroen SchuermansRobert VerkerkLinda van DiermenViolette CoppensErik FransenPeter de BoerMaarten TimmersBernard SabbeManuel Morrens

Published in: Bipolar disorders (2019)

Mania and chronic depressive symptoms in BD are accompanied by a strong interaction between inflammation and a potentially neurotoxic kynurenine metabolism.

Keyphrases

bipolar disorder
major depressive disorder
depressive symptoms
oxidative stress
sleep quality
social support
physical activity