Foveal photoreceptors loss and then recovery after treatment in a chronic myelogenous leukemia patient.
Ning-Yi HsiaChun-Ju LinHui-Ju LinKang-Hsi WuPublished in: Pediatric hematology and oncology (2020)
We report a 10-year-old boy with chronic myelogenous leukemia (CML)-related retinopathy of the eyes. Foveal photoreceptors loss was noted in the right eye, but it was restored with a continued ellipsoid zone after systemic 6-week imatinib mesylate and hydroxyurea treatment. Spectral-domain optical coherence tomography images of the foveal photoreceptors change in the right eye were taken. His best-corrected visual acuity of the right eye recovered from 20/100 to 20/20. Prompt treatment of the underlying CML could result in improvement or resolution of the ocular findings, and even foveal photoreceptors loss might be reversible with good visual acuity recovery.
Keyphrases
- optical coherence tomography
- diabetic retinopathy
- optic nerve
- chronic myeloid leukemia
- acute myeloid leukemia
- randomized controlled trial
- case report
- magnetic resonance imaging
- drug induced
- clinical trial
- computed tomography
- convolutional neural network
- sickle cell disease
- smoking cessation
- replacement therapy
- dual energy