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Human Diseased Articular Cartilage Contains a Mesenchymal Stem Cell-Like Population of Chondroprogenitors with Strong Immunomodulatory Responses.

Paola De LucaDimitrios KouroupisMarco ViganoCarlotta Perucca-OrfeiLee KaplanLuigi ZagraLaura de GirolamoDiego CorreaAlessandra Colombini
Published in: Journal of clinical medicine (2019)
based on the observed features, CCs obtained from pathological joints may constitute a potential tissue-specific therapeutic target or agent to improve damaged cartilage healing, especially damage caused by inflammatory/immune mediated conditions.
Keyphrases
  • mesenchymal stem cells
  • endothelial cells
  • oxidative stress
  • induced pluripotent stem cells
  • pluripotent stem cells
  • umbilical cord
  • cell therapy
  • risk assessment