Tumour necrosis factor inhibitor use during pregnancy is associated with increased birth weight of rheumatoid arthritis patients' offspring.
Hieronymus T W SmeeleEsther RöderAnnemarie G M G J MuldersEric A P SteegersRadboud J E M DolhainPublished in: Annals of the rheumatic diseases (2022)
This is the first study to show that TNFi use during pregnancy is associated with increased birth weight of offspring of women with well-controlled RA. The underlying mechanism of TNF-inhibition on birth weight and the long-term consequences for the offspring should be explored in future research.