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Tumour necrosis factor inhibitor use during pregnancy is associated with increased birth weight of rheumatoid arthritis patients' offspring.

Hieronymus T W SmeeleEsther RöderAnnemarie G M G J MuldersEric A P SteegersRadboud J E M Dolhain
Published in: Annals of the rheumatic diseases (2022)
This is the first study to show that TNFi use during pregnancy is associated with increased birth weight of offspring of women with well-controlled RA. The underlying mechanism of TNF-inhibition on birth weight and the long-term consequences for the offspring should be explored in future research.
Keyphrases
  • birth weight
  • rheumatoid arthritis patients
  • gestational age
  • weight gain
  • high fat diet
  • disease activity
  • rheumatoid arthritis
  • body mass index
  • preterm birth
  • systemic lupus erythematosus
  • adipose tissue
  • type diabetes