Impact of chemotherapy regimen and sequence on the effectiveness of scalp cooling for alopecia prevention.
Cynthia Villarreal GarzaFernanda Mesa-ChavezMa Ria Alejandra Garza-LedezmaOmar Peña-CurielBertha Alejandra Martinez-CannonMauricio Canavati-MarcosServando Cardona-HuertaPublished in: Breast cancer research and treatment (2020)
SC was highly effective in preventing alopecia, particularly with taxane-based regimens. Notably, better outcomes were observed when sequential chemotherapy started with taxanes followed by anthracyclines than when the inverse order was administered, suggesting that the chemotherapy sequence, rather than chemotherapeutic agents per se, might have a more significant impact on the effectiveness of SC for the prevention of alopecia.