Macrophage-derived CCL23 upregulates expression of T-cell exhaustion markers in ovarian cancer.

Kalika KamatVenkatesh Krishnan Oliver Dorigo

Published in: British journal of cancer (2022)

Our data suggest that CCL23 produced by macrophages contributes to the immune-suppressive TME in ovarian cancer by inducing an exhausted T-cell phenotype.

Keyphrases

liver fibrosis
liver injury
poor prognosis
drug induced
adipose tissue
big data
long non coding rna