Effects of Inflammatory Factor Expression Regulated by 12/15 Lipoxygenase on Obesity-Related Nephropathy.

Nian LiuYang LiuDan DongJinyu YuHang Yuan

Published in: Nutrients (2022)

12/15-LO may regulate the expression of inflammatory factors in ORG by methylation of histones in the promoter regions of genes encoding inflammatory factors, sustaining the inflammatory phenotype of ORG.

Keyphrases

oxidative stress
poor prognosis
dna methylation
genome wide
metabolic syndrome
type diabetes
gene expression
insulin resistance
binding protein
high fat diet induced