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The influence of low-carbohydrate diets on the metabolic response to androgen-deprivation therapy in prostate cancer.

Jen-Tsan Ashley ChiPao-Hwa LinVladimir TolstikovTaofik OyekunleGloria C G AlvaradoAdela Ramirez-TorresEmily Y ChenValerie BussbergBo ChiBennett GreenwoodRangaprasad SarangarajanNiven R NarainMichael A KiebishStephen J Freedland
Published in: The Prostate (2021)
Together, LCD intervention significantly reversed many ADT-induced metabolic changes while slightly enhancing androgen reduction. Future research is needed to confirm these findings and determine whether LCD can mitigate ADT-linked comorbidities and possibly delaying disease progression by further lowering androgens.
Keyphrases
  • prostate cancer
  • randomized controlled trial
  • radical prostatectomy
  • high glucose
  • weight loss
  • drug induced
  • mesenchymal stem cells
  • oxidative stress
  • bone marrow