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Immunotherapeutic early-phase clinical trials and malignant gliomas: A single-center experience and comprehensive immunophenotyping of circulating leukocytes.

Matteo SimonelliPasquale PersicoArianna CapucettiClaudia CarenzaSara FranzeseElena LorenziAngelo DipasqualeAgnese LosurdoLaura GiordanoFederico PessinaPierina NavarriaLetterio S PolitiDomenico MavilioMassimo LocatiSilvia Della BellaArmando SantoroRaffaella Bonecchi
Published in: Neuro-oncology advances (2021)
promoter methylation identifies patients who benefit more from immunotherapy. Monitoring dynamic changes of innate immune cell populations may help to predict clinical outcomes.
Keyphrases
  • genome wide
  • dna methylation
  • clinical trial
  • immune response
  • high grade
  • gene expression
  • peripheral blood
  • flow cytometry
  • transcription factor
  • phase ii
  • randomized controlled trial
  • phase iii