Autoantigen microarrays reveal myelin basic protein autoantibodies in morphea.
Jane L ZhuRicardo T PaniaguaHenry W ChenStephanie Florez-PollackElaine KunzlerNoelle TeskeYevgeniya Byekova RainwaterQuan-Zhen LiGregory A HoslerWenhao LiDenise M O RamirezNancy L MonsonHeidi T JacobePublished in: Journal of translational medicine (2022)
A molecular classification of morphea based on distinct autoantibody biosignatures may be used to differentially classify morphea. We have identified anti-MBP as a potential antibody associated with morphea due to its increased expression in morphea compared to healthy controls and systemic sclerosis patients.