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Autoantigen microarrays reveal myelin basic protein autoantibodies in morphea.

Jane L ZhuRicardo T PaniaguaHenry W ChenStephanie Florez-PollackElaine KunzlerNoelle TeskeYevgeniya Byekova RainwaterQuan-Zhen LiGregory A HoslerWenhao LiDenise M O RamirezNancy L MonsonHeidi T Jacobe
Published in: Journal of translational medicine (2022)
A molecular classification of morphea based on distinct autoantibody biosignatures may be used to differentially classify morphea. We have identified anti-MBP as a potential antibody associated with morphea due to its increased expression in morphea compared to healthy controls and systemic sclerosis patients.
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