Evaluation of [ 11 C]UCB-A positron emission tomography in human brains.
Mengfei XiongMark LubberinkLieuwe AppelXiaotian Tsong FangTorsten DanforsEva KumlienGunnar AntoniPublished in: EJNMMI research (2024)
C]UCB-A PET imaging enables quantifying SV2A in vivo. However, its slow kinetics require a long scan duration, which is impractical with the short half-life of carbon-11. Consequently, the slow kinetics and complicated quantification methods may restrict its use in humans.