Tumor-Infiltrating Lymphocytes in Patients With Stage I Triple-Negative Breast Cancer Untreated With Chemotherapy.

Veerle C M GeurtsSara BalduzziTessa G SteenbruggenSabine C LinnSabine SieslingSunil S BadveAngela DeMicheleMichail IgnatiadisRoberto A Leon-FerreMatthew P GoetzAntonio C WolffNatalie KlarStefan MichielsSherene LoiSylvia AdamsHugo M HorlingsGabe S SonkeRoberto SalgadoMarleen Kok

Published in: JAMA oncology (2024)

Results of this study showed that patients with stage I TNBC and high level of sTILs who did not receive neoadjuvant or adjuvant chemotherapy had excellent 10-year BCSS. The findings further support the role of sTILs as integral biomarkers in prospective clinical trials of therapy optimization for this patient population.

Keyphrases

clinical trial
locally advanced
rectal cancer
case report
peripheral blood
randomized controlled trial
radiation therapy
study protocol