Tuberculosis treatment intervention trials in Africa: A cross-sectional bibliographic study and spatial analysis.
Ameer Steven-Jorg HohlfeldLindi MathebulaElizabeth D PienaarAmber Louise AbramsVittoria LutjeDuduzile Edith NdwandweTamara KredoPublished in: PloS one (2021)
By mapping African TB trials, we were able to identify potential research gaps. Many of the global north's researchers were found to be the lead authors in these African trials. Few trials tested behavioural interventions compared to drugs, and far fewer tested interventions on children compared to adults to improve TB outcomes. Lastly, funders and researchers should ensure better methodological quality reporting of trials.