Comprehensive Inherited Risk Estimation for Risk-Based Breast Cancer Screening in Women.

Nina J Mars Sini Kerminen Max TamlanderMatti PirinenEveliina JakkulaKirsimari AaltonenTuomo MeretojaSirpa Heinävaara Elisabeth Widen Samuli Ripattinull null

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)

Using real-life screening data, this study demonstrates the effectiveness of a breast cancer PRS for risk stratification, alone and combined with FH and PVs. Further research is required to evaluate their impact in a prospective risk-stratified screening program, including cost-effectiveness.

Keyphrases

randomized controlled trial
systematic review
type diabetes
pregnant women
quality improvement
skeletal muscle
electronic health record