Effects of a multidomain intervention against cognitive decline on dementia risk profiles - Results from the AgeWell.de trial.
Andrea E ZuelkeAlexander PabstMelanie LuppaAnke OeySolveig WeiseThomas FankhänelRobert P KosilekHannah SchillokChristian BrettschneiderDavid CzockBirgitt WieseJochen René ThyrianWolfgang HoffmannThomas FreseJochen GensichenHans-Helmut KönigHanna KaduszkiewiczSteffi G Riedel-HellerPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
The AgeWell.de intervention reduced dementia risk according to LIfestyle for BRAin health (LIBRA) scores. Beneficial effects on LIBRA are mainly due to changes in diet and blood pressure. A pragmatic lifestyle intervention is apt to reduce dementia risk in an at-risk population.
Keyphrases
- mild cognitive impairment
- cognitive decline
- randomized controlled trial
- blood pressure
- physical activity
- cognitive impairment
- weight loss
- metabolic syndrome
- study protocol
- cardiovascular disease
- public health
- clinical trial
- mental health
- type diabetes
- white matter
- heart rate
- phase ii
- hypertensive patients
- skeletal muscle
- resting state
- subarachnoid hemorrhage
- open label
- blood glucose