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Skeletal muscle adaptations in patients with lung cancer: Longitudinal observations from the whole body to cellular level.

Deena B SnokeEmma BellefleurHibba Tul RehmanJames A CarsonMatthew E PoynterKim L DittusMichael J Toth
Published in: Journal of cachexia, sarcopenia and muscle (2023)
This study is the first to comprehensively examine longitudinal alterations in skeletal muscle fibre size and function in patients with NSCLC and suggests that muscle fibre atrophy occurs during cancer treatment despite weight stability and no changes in conventional clinical measurements of whole body or thigh muscle size over this period.
Keyphrases
  • skeletal muscle
  • insulin resistance
  • small cell lung cancer
  • cross sectional
  • body mass index
  • physical activity
  • weight gain
  • high intensity
  • adipose tissue
  • epidermal growth factor receptor