Breast cancer polygenic risk scores are associated with short-term risk of poor prognosis breast cancer.
Anne Marie McCarthyAlisa K ManningSarah HsuMichaela WelchBeverly MoyConstance D LehmanKatrina ArmstrongPublished in: Breast cancer research and treatment (2022)
Breast cancer PRS was independently and significantly associated with diagnosis of both breast cancer overall and poor prognosis breast cancer within 2 years of a negative mammogram, suggesting PRS may help guide decisions about screening intervals and supplemental screening.