Clinical outcomes and impact of therapeutic intervention in patients with acute myeloid leukemia who experience measurable residual disease (MRD) recurrence following MRD-negative remission.
Nicholas James ShortWalid MacaronTapan Mahendra KadiaCourtney D D DiNardoGhayas C IssaNaval G DaverSa WangJeff JorgensenDaniel NguyenAram BidikianKeyur P PatelSanam LoghaviMarina Y KonoplevaMusa YlimazElias J JabbourAbhishek MaitiHussein A AbbasElizabeth ShpallUday PopatGheath Al-AtrashSherry PierceHagop M KantarjianFarhad RavandiPublished in: American journal of hematology (2022)
Recurrence of MRD in AML is associated with imminent relapse unless intervened upon. Change in chemotherapy regimen and/or immediate transplant improve outcomes.