Multimodal imaging in early onset non-neovascular pigment epithelial detachments.
Mathilde M GoudotPierre-Raphael RothschildGautier BautersAldo VaggeAlexandra MiereEric H SouiedFrancine Behar-CohenFederico BernabeiPublished in: European journal of ophthalmology (2023)
The peculiar characteristics of the presented cases suggest that specific pathogenetic mechanisms, not necessarily related to age related macular degeneration, may play a key role in the development of these lesions. Whether early onset of such drusenoid PED is a specific entity resulting from a genetic deficit of lipid transporters in the RPE is unknown. Further genetic and metabolic studies should be conducted.