PRCP is a promising drug target for intracranial aneurysm rupture supported via multi-omics analysis.

Jinghao WuYunyun MeiXinYu LiWen-Kai YuZi Han ZhouYinghao YangPengpeng NiuYun-Chao Wang Chang-He ShiHanghang ZhuWenjun HeYuan GaoYu-Ming Xu Yu-Sheng Li

Published in: Stroke and vascular neurology (2024)

This study supports that elevated PRCP gene expression in blood is causally associated with the decreased risk of IA rupture. Conversely, increased PSMA4 expression in the blood is causally related to an increased risk of IA rupture and formation.

Keyphrases

gene expression
poor prognosis
dna methylation
pet ct
coronary artery
single cell
pet imaging
emergency department
computed tomography
long non coding rna
abdominal aortic aneurysm
optical coherence tomography