PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma.

Jun-Cheng WangDong-Ping ChenShi-Xun LuJin-Bin ChenYuan WeiXue-Chao LiuYu-Hao TangRong-Xin Zhang Jian-Cong ChenAnna KanLi XuYao-Jun ZhangJiajie HouDong-Ming KuangMin-Shan ChenZhong-Guo Zhou

Published in: Cancer research (2022)

Cross-talk between T cells and macrophages regulates cancer cell PIM2 expression to promote cancer aggressiveness, revealing translational approaches to improve response to ICB in hepatocellular carcinoma.

Keyphrases

poor prognosis
papillary thyroid
binding protein
signaling pathway
squamous cell carcinoma
lymph node metastasis
childhood cancer