Genetic impacts on DNA methylation help elucidate regulatory genomic processes.

Sergio VillicañaJuan Castillo-FernandezEilis HannonColette ChristiansenPei-Chien TsaiJane MaddockDiana KuhMatthew SudermanChristine PowerCaroline ReltonGeorge PloubidisAndrew WongRebecca HardyAlissa GoodmanKen K OngJordana T Bell

Published in: Genome biology (2023)

Our findings improve the characterisation of the mechanisms underlying DNA methylation variability and are informative for prioritisation of GWAS variants for functional follow-ups. The MeQTL EPIC Database and viewer are available online at https://epicmeqtl.kcl.ac.uk .

Keyphrases

dna methylation
copy number
genome wide
gene expression
social media
transcription factor
health information
cross sectional
healthcare
genome wide association study
electronic health record