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Analysis of Axin2 expression and function in murine models for pancreatic cancer.

Dietmar ZechnerTim KroemerAnn-Christin AlbertMaria SchönroggeTobias RadeckeBrigitte Vollmar
Published in: Cell & bioscience (2016)
These data demonstrate that the Wnt signaling pathway is activated during acinar-to-ductal metaplasia after injury to the pancreas. However these data do not support a major role of Wnt signaling or of Axin2 in carcinoma associated fibroblasts and tumor growth.
Keyphrases
  • signaling pathway
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  • big data
  • poor prognosis
  • stem cells
  • pi k akt
  • machine learning