Natural history of non-functioning pituitary microadenomas - results from the UK NFPA consortium.
Ross HamblinAthanasios FountasKirstie LithgowPaul Benjamin LoughreyEfstathios BonanosShah Khalid ShinwariKirsten MitchellSyed ShahLydia GrixtiMike MatheouKristina IsandDavid S McLarenAshutosh SuryaHafiz Zubair UllahKatarina KlaucaneAnuradha JayasuriyaSumbal BhattiAkash MavilakandyMasato AhsanSusan MathewZiad HusseinThijs JanszWunna WunnaJames MacFarlaneJohn AyukPrakash AbrahamWilliam M DrakeMark GurnellAntonia BrookeStephanie E BaldewegAmir H SamNiamh MartinClaire HighamNarendra ReddyMiles J LevyRupa AhluwaliaJohn Newell-PriceJoannis VamvakopoulosAmutha KrishnanAndrew LansdownRobert D MurrayAparna PalKarin BradleyYaasir MamoojeeTejpal PurewalJanki PanickerE Marie FreelFaisal HasanMohit KumarBiju JoseSteven J HunterNiki KaravitakiPublished in: European journal of endocrinology (2023)
Probability of micro-NFPA growth is low and development of new hypopituitarism is rare. Delaying first follow-up MRI to three years and avoiding hormonal re-evaluation in absence of tumour growth or clinical manifestations is a safe approach for micro-NFPA surveillance.