Comparing the Efficacy and Safety of Low-Carbohydrate Diets with Low-Fat Diets for Type 2 Diabetes Mellitus Patients: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Shunhua LiLu DingXinhua XiaoPublished in: International journal of endocrinology (2021)
LCDs are superior to LFDs for T2DM patients in improving HbA1c and reducing body weight, with a rewarding effect of some cardiovascular risk factors in a longer-term diabetes management. However, available data are insufficient to evaluate the association between diet interventions and renal safety. Future larger longer-term follow-up clinical trials are needed to provide more evidence about the sustainable effects and safety of LCDs compared with LFDs.
Keyphrases
- cardiovascular risk factors
- end stage renal disease
- clinical trial
- ejection fraction
- body weight
- newly diagnosed
- chronic kidney disease
- cardiovascular disease
- prognostic factors
- weight loss
- physical activity
- preterm infants
- metabolic syndrome
- glycemic control
- randomized controlled trial
- adipose tissue
- skeletal muscle
- big data
- deep learning
- open label
- patient reported